The Journal

Clinical notes, peptide science, and protocol design — in public.

Everything we know about apitoxin we learned by writing it down. Search by molecule, system, or clinical topic.

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10 posts

Clinical registry

Molecular

The Science of Melittin

How a 26-amino-acid peptide became the most studied molecule in clinical apitherapy — and why purity below 99.9% is medically meaningless.

#melittin#purity#chromatography
Mar 202618 min
Molecular

Apamin and the Quiet Analgesia

The 18-residue peptide that blocks SK channels with surgical specificity — and why it is the unsung half of every BSerum dose.

#apamin#sk-channel#analgesia
Feb 202614 min
Molecular

Phospholipase A₂: The Enzyme We Keep

PLA₂ is the immunologically loudest component of bee venom. Most apitherapy programmes try to remove it. We standardise it to 0.6% — and the data explains why.

#pla2#immunology#hormesis
Feb 202615 min
Engineering

AI Dosimetry: The Architecture of Zero Harm

Inside the closed-loop control system that adjusts every BSerum dose in real time across 14 biomarkers — and why the model does not get to decide alone.

#ai#guardian#dosimetry
Jan 202622 min
Clinical

12,400 Sessions, Zero Adverse Events

The registry behind the headline number — what we measured, how we adjudicated, and what we still do not know.

#registry#safety#adjudication
Jan 202617 min
Dermatology

Skin as an Organ of Immune Memory

Why the topical protocol works on conditions we historically treated systemically — and what the dermal microenvironment is actually doing.

#skin#trm#fibroblast
Dec 202513 min
Protocol

The Geneva Protocol: Design Notes

Why our 30-day initiation looks the way it does — and the four things we changed after the first 400 patients told us we were wrong.

#protocol#initiation#iteration
Nov 202516 min
Field Notes

What Bee Venom Is Not

A short, blunt guide to the marketing claims, folk remedies, and overconfident influencer pitches that have nothing to do with clinical apitherapy.

#myth-busting#marketing#patient-safety
Nov 202510 min
Regulatory

Regulatory Status: EU MDR Class IIa

What our classification actually means, what it does not mean, and what we are working toward in 2026.

#mdr#ce-mark#samd
Oct 202512 min
Clinical

Patient Stories, With Receipts

Three anonymised patient journeys reconstructed entirely from signed session telemetry — no testimonials, no editing, just the data and what it shows.

#patient-outcomes#telemetry#psoriasis
Oct 202516 min